Nurse Practitioners Salary in San Francisco, CA
BLS Occupational Employment & Wage Statistics • May 2025 • San Francisco-Oakland-Fremont, CA
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In San Francisco, CA, nurse practitioners enjoy a median annual salary of $220,330, significantly higher than the national median of $129,210 for this occupation. This substantial difference highlights the premium that healthcare professionals receive in high-cost living areas like San Francisco. In comparison to local household income, which stands at an area median of $133,780, nurse practitioners earn nearly 1.65 times more, illustrating their critical role and demand within the region's healthcare sector. With a relatively low local unemployment rate of 4.20%, the job market for nurse practitioners remains robust, reflecting both the high salaries and steady employment opportunities available.
At the entry-level, nurse practitioners in San Francisco can expect to earn around $140,910 annually, which is at the 10th percentile mark. As they gain experience and expertise, their earnings potential increases significantly, with those in the 75th percentile earning approximately $234,120 each year. The difference between entry-level and experienced workers' salaries is driven by factors such as specialization within nursing, additional certifications, years of practice, and leadership roles. Experienced nurse practitioners often command higher wages due to advanced clinical skills, increased responsibilities, and possibly a broader scope of practice. Additionally, the high cost of living in San Francisco necessitates competitive compensation packages to attract and retain skilled healthcare professionals.
Salary percentile breakdown
San Francisco economic context
Frequently asked questions
How much do Nurse Practitioners make per hour in San Francisco?
The median hourly wage for Nurse Practitioners in San Francisco, CA is $105.93, based on BLS OEWS 2025 data. Top earners (90th percentile) make $131.71 or more per hour.
Is San Francisco above or below average for Nurse Practitioners salaries?
The median Nurse Practitioners salary in San Francisco, CA is 70.5% above the national median of $129,210. The national figure is from BLS OEWS 2025 data covering all US metropolitan areas.
What is the entry-level salary for Nurse Practitioners in San Francisco?
Entry-level Nurse Practitioners (10th percentile) earn around $140,910 per year in San Francisco, CA. The 25th percentile — typically workers with 1–3 years of experience — earn approximately $170,370.