Nurse Practitioners Salary in South Carolina
BLS OEWS May 2025 • 11 metro areas • South Carolina
Nurse Practitioners in South Carolina earn a median salary of $115,571 per year on average across 11 metro and nonmetro areas, -10.6% vs the national median of $129,210. An estimated 5,070 nurse practitioners are employed across South Carolina, with salaries ranging from $104,120 to $123,100 depending on location.
$115,571
Avg median salary in South Carolina
$123,100
Highest paying metro
$104,120
Lowest paying metro
5,070
Employed in South Carolina
Compare Nurse Practitioners salaries & buying power
Pick two cities to see how salary and purchasing power differ.
Nurse Practitioners
in
Nurse Practitioners salaries by city in South Carolina
| Metro area | Median salary | 25th pct | 75th pct | Employed |
|---|---|---|---|---|
| Charleston, SC | $123,100 | $106,050 | $138,880 | 1,260 |
| Florence, SC | $121,670 | $103,800 | $134,000 | 280 |
| Southern South Carolina | $119,300 | $99,430 | $133,100 | 170 |
| Myrtle Beach, SC | $117,750 | $103,080 | $124,660 | 280 |
| Northeastern South Carolina | $117,040 | $103,140 | $127,140 | 190 |
| Spartanburg, SC | $116,740 | $105,610 | $133,590 | 250 |
| Hilton Head Island, SC | $116,500 | $99,240 | $129,440 | 220 |
| Northwestern South Carolina | $112,460 | $102,370 | $122,920 | 260 |
| Columbia, SC | $112,050 | $106,590 | $132,240 | 960 |
| Greenville, SC | $110,550 | $101,260 | $123,930 | 1,130 |
| Sumter, SC | $104,120 | $101,480 | $120,420 | 70 |