Physician Assistants Salary in Sioux Falls, SD-MN

BLS Occupational Employment & Wage Statistics • May 2025 • Sioux Falls, SD-MN

Median annual salary $128,130 -3.8% vs national
Median hourly $61.60
10th percentile $106,720
90th percentile $154,050
Employed locally 280
National median $133,260

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Physician Assistants
in
Sioux Falls, SD-MN
vs

    Salary percentile breakdown

    10th
    $106,720
    25th
    $122,680
    50th (median)
    $128,130
    75th
    $141,420
    90th
    $154,050

    Sioux Falls economic context

    Unemployment rate 1.70% 2024 annual avg • BLS LAUS
    Median household income $81,418 2023 • Census ACS
    Physician Assistants salary vs area income 157% Median Physician Assistants salary is 57% above the area median household income

    Top-paying metros for Physician Assistants

    Metro areaMedian salary
    San Jose-Sunnyvale-Santa Clara, CA $215,600
    Napa, CA $183,930
    Vallejo, CA $180,540
    Modesto, CA $178,520
    Massachusetts nonmetropolitan area $167,140
    San Francisco-Oakland-Fremont, CA $167,090

    Nearby metros — Physician Assistants salary comparison

    Metro areaMedian salary
    Sioux City, IA-NE-SD $126,500
    Rapid City, SD $122,160

    Related occupations in Sioux Falls, SD-MN

    OccupationMedian salary
    Registered Nurses $68,890
    Licensed Practical and Licensed Vocational Nurses $49,310
    Pharmacists $143,000
    Clinical Laboratory Technologists and Technicians $55,870
    Pharmacy Technicians $44,160
    Nurse Practitioners $130,580

    Frequently asked questions

    How much do Physician Assistants make per hour in Sioux Falls?

    The median hourly wage for Physician Assistants in Sioux Falls, SD-MN is $61.60, based on BLS OEWS 2025 data. Top earners (90th percentile) make $76.21 or more per hour.

    Is Sioux Falls above or below average for Physician Assistants salaries?

    The median Physician Assistants salary in Sioux Falls, SD-MN is 3.8% below the national median of $133,260. The national figure is from BLS OEWS 2025 data covering all US metropolitan areas.

    What is the entry-level salary for Physician Assistants in Sioux Falls?

    Entry-level Physician Assistants (10th percentile) earn around $106,720 per year in Sioux Falls, SD-MN. The 25th percentile — typically workers with 1–3 years of experience — earn approximately $122,680.