Registered Nurses Salary in Charleston, SC
BLS Occupational Employment & Wage Statistics • May 2025 • Charleston-North Charleston, SC
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In Charleston, SC, registered nurses earn a median annual salary of $80,620, which is slightly below the national median of $93,600 for this occupation. The typical nurse in the area earns an hourly wage of $38.76. When compared to the local median household income of $82,272, the earnings of registered nurses are fairly aligned, indicating that their salaries contribute significantly to the financial stability of households in Charleston. This alignment suggests that nursing is a vital profession within the community, providing economic support comparable to other household incomes.
For entry-level registered nurses in Charleston, SC, starting salaries can be as low as $70,410, which represents the 10th percentile, while those at the 25th percentile earn approximately $78,050. As nurses gain experience and move up to the 75th percentile, their earnings increase significantly to about $97,660 annually, with top earners in the 90th percentile making around $100,700 per year. The difference in pay between entry-level and experienced nurses is driven by several factors, including years of service, advanced certifications, specialized skills, and roles that require greater responsibility or management duties. These elements collectively contribute to the progression in earnings throughout a nurse's career.
Salary percentile breakdown
Charleston economic context
Frequently asked questions
How much do Registered Nurses make per hour in Charleston?
The median hourly wage for Registered Nurses in Charleston, SC is $38.76, based on BLS OEWS 2025 data. Top earners (90th percentile) make $56.68 or more per hour.
Is Charleston above or below average for Registered Nurses salaries?
The median Registered Nurses salary in Charleston, SC is 13.9% below the national median of $93,600. The national figure is from BLS OEWS 2025 data covering all US metropolitan areas.
What is the entry-level salary for Registered Nurses in Charleston?
Entry-level Registered Nurses (10th percentile) earn around $70,410 per year in Charleston, SC. The 25th percentile — typically workers with 1–3 years of experience — earn approximately $78,050.