Registered Nurses Salary in Greenville, SC
BLS Occupational Employment & Wage Statistics • May 2025 • Greenville-Anderson-Greer, SC
Median annual salary
$79,580
-15% vs national
Median hourly
$38.26
10th percentile
$66,020
90th percentile
$98,290
Employed locally
9,460
National median
$93,600
Compare Registered Nurses salary & buying power
Type a city below to see how Greenville, SC stacks up on salary and cost of living.
Registered Nurses
inGreenville, SC
vsSalary percentile breakdown
Greenville economic context
Unemployment rate
3.80%
2024 annual avg • BLS LAUS
Median household income
$69,016
2023 • Census ACS
Registered Nurses salary vs area income
115%
Median Registered Nurses salary is 15% above the area median household income
Frequently asked questions
How much do Registered Nurses make per hour in Greenville?
The median hourly wage for Registered Nurses in Greenville, SC is $38.26, based on BLS OEWS 2025 data. Top earners (90th percentile) make $48.38 or more per hour.
Is Greenville above or below average for Registered Nurses salaries?
The median Registered Nurses salary in Greenville, SC is 15% below the national median of $93,600. The national figure is from BLS OEWS 2025 data covering all US metropolitan areas.
What is the entry-level salary for Registered Nurses in Greenville?
Entry-level Registered Nurses (10th percentile) earn around $66,020 per year in Greenville, SC. The 25th percentile — typically workers with 1–3 years of experience — earn approximately $75,550.