Registered Nurses Salary in Southern Indiana

In Southern Indiana, the typical registered nurse earns a median annual salary of $78,450, which translates to approximately $37.72 per hour. This figure is notably below the national median for registered nurses, which stands at $93,600 as reported by the BLS OEWS May 2025 data. When compared to local household incomes in Southern Indiana, a nurse's earnings are generally competitive, given that they align closely with many middle-income professional roles within the region. The disparity between the regional and national figures might reflect differences in living costs or demand for nursing professionals in this locale.

Entry-level registered nurses in Southern Indiana typically earn around $58,860 annually, which is at the 10th percentile of earnings. In contrast, those who have gained experience and are working towards higher percentiles can earn significantly more; by the 25th percentile, salaries rise to about $67,600, while experienced professionals at the 75th percentile may see annual incomes reaching approximately $82,170. The top earners in this field, at the 90th percentile, can make as much as $96,640 annually. This salary progression is driven largely by factors such as years of experience, specialization, and responsibilities within healthcare institutions. Additional influences include geographic demand for nurses, institutional size, and availability of advanced certifications or education credentials.