Physician Assistants Salary in St. Louis, MO-IL

BLS Occupational Employment & Wage Statistics • May 2025 • St. Louis, MO-IL

Median annual salary $140,240 +5.2% vs national
Median hourly $67.42
10th percentile $74,670
90th percentile $169,980
Employed locally 790
National median $133,260

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Physician Assistants
in
St. Louis, MO-IL
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    Salary percentile breakdown

    10th
    $74,670
    25th
    $116,790
    50th (median)
    $140,240
    75th
    $161,840
    90th
    $169,980

    St. Louis economic context

    Unemployment rate 3.70% 2024 annual avg • BLS LAUS
    Median household income $78,225 2023 • Census ACS
    Physician Assistants salary vs area income 179% Median Physician Assistants salary is 79% above the area median household income

    Top-paying metros for Physician Assistants

    Metro areaMedian salary
    San Jose-Sunnyvale-Santa Clara, CA $215,600
    Napa, CA $183,930
    Vallejo, CA $180,540
    Modesto, CA $178,520
    Massachusetts nonmetropolitan area $167,140
    San Francisco-Oakland-Fremont, CA $167,090

    Nearby metros — Physician Assistants salary comparison

    Metro areaMedian salary
    Modesto, CA $178,520
    San Francisco-Oakland-Fremont, CA $167,090
    North Valley-Northern Mountains Region of California nonmetropolitan area $164,750
    Eastern Sierra-Mother Lode Region of California nonmetropolitan area $160,310
    Joplin, MO-KS $152,550
    Atlantic City-Hammonton, NJ $148,200

    Related occupations in St. Louis, MO-IL

    OccupationMedian salary
    Registered Nurses $82,560
    Licensed Practical and Licensed Vocational Nurses $62,540
    Clinical Laboratory Technologists and Technicians $54,740
    Pharmacy Technicians $40,030
    Nurse Practitioners $129,390
    Pharmacists $137,730

    Frequently asked questions

    How much do Physician Assistants make per hour in St. Louis?

    The median hourly wage for Physician Assistants in St. Louis, MO-IL is $67.42, based on BLS OEWS 2025 data. Top earners (90th percentile) make $82.19 or more per hour.

    Is St. Louis above or below average for Physician Assistants salaries?

    The median Physician Assistants salary in St. Louis, MO-IL is 5.2% above the national median of $133,260. The national figure is from BLS OEWS 2025 data covering all US metropolitan areas.

    What is the entry-level salary for Physician Assistants in St. Louis?

    Entry-level Physician Assistants (10th percentile) earn around $74,670 per year in St. Louis, MO-IL. The 25th percentile — typically workers with 1–3 years of experience — earn approximately $116,790.