Registered Nurses Salary in St. Louis, MO-IL

In St. Louis, MO-IL, registered nurses (RNs) earn a median annual salary of $82,560, with a median hourly wage of $39.69. This figure stands below the national median for RNs, which is $93,600, reflecting regional cost-of-living differences and labor market conditions. When compared to local household incomes, the median earnings of an RN surpass the area’s median household income of $78,225. This suggests that registered nurses in this region are typically earning more than the average household, indicating their critical role and high demand within the healthcare industry, especially given a relatively low unemployment rate of 3.70%.

At entry-level positions, registered nurses in St. Louis generally earn around $61,990 annually, which is at the 10th percentile of earnings for this occupation. As they gain experience, RNs can expect substantial salary increases; those in the 25th percentile earn approximately $68,760, and those near the top (75th percentile) make about $96,780 per year. The most experienced nurses can reach salaries up to $105,630 annually, at the 90th percentile. These differences are driven by factors such as tenure, specialization, additional certifications, and shifts in demand for specific nursing skills or specialties. The substantial increase from entry-level to more seasoned roles underscores the value of experience and skill development within the nursing profession.