Registered Nurses Salary in South Carolina
BLS OEWS May 2025 • 11 metro areas • South Carolina
Registered Nurses in South Carolina earn a median salary of $79,939 per year on average across 11 metro and nonmetro areas, -14.6% vs the national median of $93,600. An estimated 45,880 registered nurses are employed across South Carolina, with salaries ranging from $77,640 to $82,680 depending on location.
$79,939
Avg median salary in South Carolina
$82,680
Highest paying metro
$77,640
Lowest paying metro
45,880
Employed in South Carolina
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Registered Nurses salaries by city in South Carolina
| Metro area | Median salary | 25th pct | 75th pct | Employed |
|---|---|---|---|---|
| Myrtle Beach, SC | $82,680 | $71,770 | $83,390 | 3,110 |
| Charleston, SC | $80,620 | $78,050 | $97,660 | 9,560 |
| Southern South Carolina | $80,420 | $75,860 | $98,480 | 1,060 |
| Sumter, SC | $80,240 | $70,160 | $87,460 | 700 |
| Florence, SC | $80,220 | $64,780 | $111,060 | 3,060 |
| Columbia, SC | $80,100 | $75,460 | $96,140 | 9,800 |
| Northwestern South Carolina | $79,800 | $72,620 | $86,350 | 1,860 |
| Greenville, SC | $79,580 | $75,550 | $93,500 | 9,460 |
| Spartanburg, SC | $79,550 | $67,850 | $84,210 | 4,660 |
| Hilton Head Island, SC | $78,480 | $66,240 | $87,460 | 1,420 |
| Northeastern South Carolina | $77,640 | $66,670 | $86,500 | 1,190 |